Towards Developing a Screening Strategy for Ecstasy: Revealing the Electrochemical Profile

This article describes the development of an electrochemical screening strategy for 3,4-methylenedioxymethamphetamine (MDMA), regular psychoactive compound in ecstasy (XTC) pills. We have investigated specific profile MDMA and its electro-oxidation mechanisms at disposable graphite screen-printed electrodes. proved that formation a radical cation subsequent reactions are indeed responsible electrode surface passivation, as evidenced by using electron paramagnetic resonance spectroscopy electrochemistry. Thereafter, pure cutting agents well simulated binary mixtures compounds with were subjected to square wave voltammetry pH 7 understand characteristic profile. An additional measurement 12 was able resolve false positives negatives occurring 7. Finally, validation done measuring set street samples. Overall, our proposed has been demonstrated rapid, sensitive, selective detection MDMA, resolving most given traditional Marquis color tests, thus exhibiting remarkable promises on-site MDMA.